J. Craig Venter, the genome pioneer, has created a “synthetic cell” by synthesizing a complete bacterial genome and using it to take over a cell. Venter’s breakthrough, reported in the online edition of Science, represents a preliminary step toward the goal of creating microbes from scratch in the lab and using them to make biofuels, vaccines, and other products.

Venter’s achievement could one day lead to a technology where, though engineering the genome, individual cells could be turned into their own miniature refineries for harvesting carbon dioxide and generating hydrocarbons.

In 2005, Venter — one of the first people to sequence the human genome, doing it faster and cheaper than government scientists — set up a company, Synthetic Genomics, to create synthetic cells, and the advance reported in Science represents a milestone for the company and for so-called synthetic biology.

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